Six separate ageing clocks, run on the same 43 patients, all pointed in the same direction: younger predicted biological age after 12 weeks on an experimental drug.

The drug, rentosertib, was built by Insilico Medicine to treat idiopathic pulmonary fibrosis, a scarring lung disease with no cure. Its anti-ageing signal showed up almost as a side finding.

Rentosertib's molecular structure was generated using Insilico's Chemistry42 platform, the same category of AI technique behind image generators and chatbots.

Ageing clocks work........

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