Speedballing – the practice of combining a stimulant like cocaine or methamphetamine with an opioid such as heroin or fentanyl – has evolved from a niche subculture to a widespread public health crisis. The practice stems from the early 1900s when World War I soldiers were often treated with a combination of cocaine and morphine.

Once associated with high-profile figures like John Belushi, River Phoenix and Chris Farley , this dangerous polysubstance use has become a leading cause of overdose deaths across the United States since the early- to mid-2010s.

I am an assistant professor of public health who has written extensively on methamphetamine and opioid use and the dangerous combination of the two in the United States.

As these dangerous combinations of drugs increasingly flood the market, I see an urgent need and opportunity for a new approach to prevention and treatment.

Dating back to the 1970s, the term speedballing originally referred to the........

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