For 20-year-old Mayank Yadav, riding a crowded bus in the summer months in this western Indian city can be like sitting in an oven. That makes it a treat when he steps off and into a bus stop outfitted with sprinklers that bathe overheated commuters in a cooling mist.

“Everyone is suffering from the heat,” Yadav said. “I hope they do more of this across the city.”

Rising heat is a problem for millions of people in India. In Ahmedabad, temperatures this year have already reached 42 degrees Celsius (107 Fahrenheit), a level usually not seen for several more weeks, prompting city officials to advise people to stay indoors and stay hydrated.

And yet, coping with that heat is a familiar challenge in Ahmedabad. After a 2010 heat wave killed more than 1,300 people, city and health officials rushed to develop South Asia’s first heat action plan.

The plan, rolled out in 2013 and now replicated across India and South Asia, includes strategies for hospitals, government officials and citizens to react immediately when temperatures rise beyond human tolerance. Public health officials said it’s helped save hundreds of lives every summer.

City officials, with help from climate and health researchers, have........

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