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GLP-1s may work by activating an unlikely weight loss ally

19 0
01.09.2026

GLP-1s may work by activating an unlikely weight loss ally

(NewsNation) — A brain cell once thought to be an obstacle to weight loss may actually be the key to maintaining it.

Scientists at Yale were studying how GLP-1s work inside the brain, specifically how their main ingredient, semaglutide, helps sustain weight loss. They published their findings in the journal Proceedings of the National Academy of Sciences in July.

They discovered that a neuron known for stimulating hunger, called agouti-related peptide (AgRP), is actually triggered into overdrive by semaglutide. But instead of increasing hunger, it began helping the body burn more fat at rest.

Research in........

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