If you spend any time on social media, you may have noticed a curious trend: wellness influencers singing the praises of nicotine. Not smoking or vaping but nicotine patches and pouches, repackaged as cognitive enhancers, productivity boosters and even weight-loss aids. But does the science support this rebrand, or are we watching a familiar substance undergo a very modern makeover?

Nicotine is primarily a stimulant and derived from the tobacco plant. Small amounts of nicotine are also found in other members of the nightshade family, including tomatoes, aubergines, potatoes and green peppers. However, the levels in these foods are minimal compared with those in tobacco.

Nicotine works by latching on to specific receptors found throughout the body, triggering the release of various brain chemicals such as dopamine, noradrenaline, and serotonin. These receptors, along with a chemical messenger called acetylcholine, play an important role in attention, learning and memory.

The evidence on whether nicotine can enhance cognitive performance is mixed. One large review of 41 trials involving healthy adults – both non-smokers and smokers – found that nicotine produced small improvements in areas such as fine motor skills, attention and aspects of........

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