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Senate Republicans voted in the early hours of Thursday morning to reject an amendment offered by Sen. Bernie Sanders that aimed to cut US prescription drug prices in half by mandating that Americans pay no more for medications than people in Canada and other wealthy nations.

Just two Republicans, Sens. Josh Hawley of Missouri and Dan Sullivan of Alaska, voted with every present Democrat in support of Sanders’ (I-Vt.) proposed amendment to the GOP’s emerging budget reconciliation package. Republicans plan to use the legislative vehicle to fund the Department of Homeland Security and its component agencies, principally Immigration and Customs Enforcement (ICE) and Customs and Border Protection (CBP).

The amendment vote put nearly every Senate Republican on the record against a policy supported by President Donald Trump. Last year, Trump signed an executive order directing federal health officials to “communicate most-favored-nation price targets to pharmaceutical manufacturers to bring prices for American patients in line with comparably developed nations.”

But experts have noted that, without congressional action giving the federal government more power over drug pricing,........

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