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Understanding the difference between apathy and depression can be lifesaving for people with brain disorders

6 0
12.02.2026

People with brain disorders, including Parkinson’s disease and dementia, are often misdiagnosed as having depression, when in fact what they’re experiencing is apathy. This can delay an accurate diagnosis, which has negative outcomes for patients as well as for their families and caregivers.

Apathy and depression may look alike from the outside, but they arise from different neurobiological pathways and have different implications for treatment, functioning and quality of life for those affected.

Understanding and identifying the differences is crucial. My recent research focused on developing a simple assessment tool to differentiate apathy from depression.

Brain disorders, particularly Alzheimer’s disease and other dementias, as well as Parkinson’s disease, are common in Canada.

According to a 2017 Public Health Agency of Canada (PHAC) report, an estimated 3.6 million Canadians have been diagnosed with brain disorders. More recently, the Canadian Brain Research Strategy estimates that one in five Canadians is affected by these conditions, with a total estimate of more than 7.5 million people currently living with brain conditions.

As the Canadian population ages due to demographic shifts and improved survival rates from once-fatal illnesses, the number of people living with these disorders will increase significantly.

As of January 2025, dementia alone affected 771,939 Canadians aged 65 and older. The prevalence of dementia increases with age. The likelihood of a diagnosis more than doubles every five years after age 65. We can therefore expect more than........

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