The youngest-ever female Fortune 500 CEO is reinventing the largest Medicaid insurer amid funding cuts and rising costs

In today’s CEO Daily: Diane Brady profiles Centene CEO Sarah London.

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Good morning. Sarah London, the youngest-ever female CEO to run a Fortune 500 company, isn’t leading from a place of comfort. As federal cuts and new regulations reshape U.S. health care, the chief executive of Centene, the country’s biggest Medicaid insurer, is redefining what it means to innovate in a constrained environment. Her playbook is less about bold spending and more about disciplined reinvention; she’s streamlining operations, shedding noncore businesses, and using predictive algorithms to help manage care for vulnerable populations. At a moment when “the country is getting poorer and sicker,” as she puts it, London’s version of innovation is all about using technology to keep the social safety net intact. (You can read my full story on her here.)

Centene grew revenue almost 20% last year amid drastic cuts to federal Medicaid spending that have inflicted pain on the bottom line and customers. That hasn’t stopped London from focusing on programs that tie affordable housing to health care or leveraging AI to identify and deliver a suite of........

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