Former Senate Republican Leader Mitch McConnell (Ky.) on Monday called Sen. Thom Tillis’s (R-N.C.) surprise announcement that he will not run for reelection a “big setback” for Senate Republicans, as political handicappers now think Democrats have a better chance of flipping the North Carolina Senate seat.

McConnell posted on the social platform X that Tillis “is one of the most effective and collegial members that I have ever served with in the United States........

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