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The Problem of Post-SSRI Sexual Dysfunction

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30.07.2026

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The Problem of Post-SSRI Sexual Dysfunction

Jennifer Galardi | Gabriella DiPrima

A 21-year-old college student struggles to sleep during finals month. On a friend’s recommendation, she decides to seek out a sleep aid. She books a telehealth appointment through an app she saw advertised on Instagram. It’s covered by her insurance and only takes about 3 minutes to set up a therapy session via an AI chatbot. By the end of a 10-minute conversation, a psychiatrist prescribes a selective serotonin reuptake inhibitor (SSRI), capable of undermining her sexual function for life without so much as a fine-print warning. 

This is the scenario that the psychiatric and pharmaceutical worlds have made so readily accessible to Americans for easy profit and with little concern over an ignored side effect: Post-SSRI Sexual Dysfunction (PSSD).  

SSRIs make up about 70% of antidepressant prescriptions and are consumed by tens of millions of Americans every day. From 2006 to 2023, the number of U.S. children and adolescents ages 3-17 receiving SSRIs has more than doubled.  

The increasingly popular drugs block the process of the chemical messenger serotonin being taken back into brain cells, increasing the amount........

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